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Products Details
Product Description
– Toxoflavin-13C4 is the 13C-labeled Toxoflavin. Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor activity[1][2]. Antibiotic properties.
Web ID
– HY-100760S
Shipping
– Room temperature
Molecular Formula
– C3 13C4H6N5O2
References
– [1]Wei W, et al. Small molecule antagonists of Tcf4/beta-catenin complex inhibit the growth of HCC cells in vitro and in vivo. Int J Cancer. 2010 May 15;126(10):2426-36.|[2]Franci G, et al. Identification and characterization of PKF118-310 as a KDM4A inhibitor. Epigenetics. 2017 Mar 4;12(3):198-205.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 2300178-70-3
Molecular Weight
– 196.13
SMILES
– O=[13C]([13C]1=N[13C]=NN(C)[13C]1=N2)N(C)C2=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Bacterial;Isotope-Labeled Compounds;β-catenin
Pathway
– Anti-infection;Others;Stem Cell/Wnt
Product type
– Isotope-Labeled Compounds
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