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Toxoflavin
SKU
HY-100760-10 mg
Category Reference compound
Tags Anti-infection;Stem Cell/Wnt, Antibiotic;Bacterial;β-catenin, Cancer; Infection
$110 – $390
Products Details
Product Description
– Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor activity[1][2]. Antibiotic properties.
Web ID
– HY-100760
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C7H7N5O2
References
– [1]Wei W, et al. Small molecule antagonists of Tcf4/beta-catenin complex inhibit the growth of HCC cells in vitro and in vivo. Int J Cancer. 2010 May 15;126(10):2426-36.|[2]Franci G, et al. Identification and characterization of PKF118-310 as a KDM4A inhibitor. Epigenetics. 2017 Mar 4;12(3):198-205.
CAS Number
– 84-82-2
Molecular Weight
– 193.16
Compound Purity
– 99.92
SMILES
– O=C(C1=NC=NN(C)C1=N2)N(C)C2=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– DMSO : 25 mg/mL (ultrasonic)|H2O : 10 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Antibiotic;Bacterial;β-catenin
Pathway
– Anti-infection;Stem Cell/Wnt
Product type
– Reference compound
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