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Toxoflavin
$110 – $390
Products Details
Product Description
– Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor activity[1][2]. Antibiotic properties.
Web ID
– HY-100760
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C7H7N5O2
References
– [1]Wei W, et al. Small molecule antagonists of Tcf4/beta-catenin complex inhibit the growth of HCC cells in vitro and in vivo. Int J Cancer. 2010 May 15;126(10):2426-36.|[2]Franci G, et al. Identification and characterization of PKF118-310 as a KDM4A inhibitor. Epigenetics. 2017 Mar 4;12(3):198-205.
CAS Number
– 84-82-2
Molecular Weight
– 193.16
Compound Purity
– 99.92
SMILES
– O=C(C1=NC=NN(C)C1=N2)N(C)C2=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– DMSO : 25 mg/mL (ultrasonic)|H2O : 10 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Antibiotic;Bacterial;β-catenin
Pathway
– Anti-infection;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
