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Products Details
Product Description
– Topoisomerase II inhibitor 15 (compound 2g) is a Topoisomerase II inhibitor. Topoisomerase II inhibitor 15 potently is an apoptotic inducer with greater selectivity against head and neck tumors[1].
Web ID
– HY-155645
Shipping
– Room temperature
Molecular Formula
– C15H11Cl2N5
References
– [1]Ahmed A Al-Karmalawy, et al. Novel fused imidazotriazines acting as promising top. II inhibitors and apoptotic inducers with greater selectivity against head and neck tumors: Design, synthesis, and biological assessments. Eur J Med Chem. 2023 Nov 5;259:115661.
CAS Number
– 451516-79-3
Molecular Weight
– 332.19
SMILES
– ClC1=CC=C(C2N=C(N)N=C3NC4=C(N32)C=CC=C4)C=C1Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Topoisomerase
Pathway
– Apoptosis;Cell Cycle/DNA Damage
Product type
– Reference compound
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