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Products Details
Product Description
– Topoisomerase II inhibitor 12 (Compound 8c) is a topoisomerase II (topo II) inhibitor, working as a DNA non-intercalator. Topoisomerase II inhibitor 12 shows antineoplastic activity[1].
Web ID
– HY-147877
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C40H63N3O4
References
– [1]Xie XW, et al. Design, synthesis, bioevaluation of LFC- and PA-tethered anthraquinone analogues of mitoxantrone. Bioorg Chem. 2020 Aug;101:104005.
CAS Number
– 2304527-20-4
Molecular Weight
– 649.95
SMILES
– CCCCCCCCCCCCOC1=C(C(C2=C(C3=O)C=CC=C2)=O)C3=C(C=C1)OCCCCNCCCNCCCCNCCC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Topoisomerase
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
