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Products Details
Product Description
– Topoisomerase I inhibitor 9 (compound 3d) is a leishmanial topoisomerase IB inhibitor. Topoisomerase I inhibitor 9 has antileishmanial activity against L. donovani promastigotes, with the IC50 of 34.81μM[1].
Web ID
– HY-156462
Shipping
– Room temperature
Molecular Formula
– C23H15Br2FN2
References
– [1]Kour P, et al. Design, synthesis, and biological evaluation of 3,3′-diindolylmethane N-linked glycoconjugate as a leishmanial topoisomerase IB inhibitor with reduced cytotoxicity. RSC Med Chem. 2023;14(10):2100-2114. Published 2023 Aug 30.
CAS Number
– 1228150-86-4
Molecular Weight
– 498.19
SMILES
– FC1=CC=C(C(C2=CNC3=C2C=C(Br)C=C3)C4=CNC5=C4C=C(Br)C=C5)C=C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Topoisomerase
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
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