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Product Description
– Topoisomerase I inhibitor 6 (Compound 3) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 6 is able to trap DNA-Top1 cleavage complex and found to be less cytotoxic in non-cancerous cell line. Topoisomerase I inhibitor 6 has the potential for the research of cancer diseases[1].
Web ID
– HY-146437
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H21N7O
References
– [1]Kundu B, et al. Development of a metabolically stable topoisomerase I poison as anticancer agent. Eur J Med Chem. 2020 Sep 15;202:112551. doi: 10.1016/j.ejmech.2020.112551.
CAS Number
– 2393082-56-7
Molecular Weight
– 411.46
SMILES
– NC1=CC=C(C=C1)C2=CC=C3N=CC(C4=NN=CO4)=C(C3=C2)NCCCN5C=CN=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Topoisomerase
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
