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Products Details
Product Description
– Topoisomerase I inhibitor 10 (compound 13) is a leishmanial topoisomerase IB inhibitor. Topoisomerase I inhibitor 10 has antileishmanial activity against L. donovani promastigotes, with the IC50 of 27.91 μM[1].
Web ID
– HY-156464
Shipping
– Room temperature
Molecular Formula
– C35H35Br2FN2O10
References
– [1]Kour P, et al. Design, synthesis, and biological evaluation of 3,3′-diindolylmethane N-linked glycoconjugate as a leishmanial topoisomerase IB inhibitor with reduced cytotoxicity. RSC Med Chem. 2023;14(10):2100-2114. Published 2023 Aug 30.
Molecular Weight
– 822.47
SMILES
– FC1=CC=C(C=C1)C(C2=CN(C3=C2C=C(C=C3)Br)[C@H]4O[C@H]([C@@H]([C@@H]([C@@H]4O)O)O)CO)C5=CN(C6=C5C=C(C=C6)Br)[C@@H]7O[C@@H]([C@H]([C@H]([C@H]7O)O)O)CO
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Topoisomerase
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
