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Products Details
Product Description
– Topo II/HDAC-IN-2 (8d) exhibits excellent dual inhibitory activities against Topo II and HDAC. Topo II/HDAC-IN-2 (8d) induces apoptosis[1].
Web ID
– HY-149239
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C17H20N4O3S
References
– [1]Mengmiao Zhao,
et al. Design, synthesis and biological evaluation of dual Topo II/HDAC
inhibitors bearing pyrimido[5,4-b]indole and pyrazolo[3,4-d]pyrimidine motifs. Eur
J Med Chem. 2023 Apr 5;252:115303.
CAS Number
– 2922269-24-5
Molecular Weight
– 360.43
SMILES
– CCN1C(C2=C(C3=C(N2)C=CC=C3)N=C1SCCCCC(NO)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;HDAC;Topoisomerase
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
