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Tolterodine-d14 (hydrochloride)
$420
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Products Details
Product Description
– Tolterodine-d14 (hydrochloride) is the deuterium labeled Tolterodine hydrochloride[1]. Tolterodine hydrochloride is a potent muscarinic receptor antagonist[2][3].
Web ID
– HY-A0024S
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Molecular Formula
– C22H18D14ClNO
References
– [1]Cappon GD, et al. Tolterodine does not affect memory assessed by passive-avoidance response test in mice. Eur J Pharmacol. 2008 Jan 28;579(1-3):225-8.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[3]Nilvebrant L. Tolterodine and its active 5-hydroxymethyl metabolite: pure muscarinic receptor antagonists. Pharmacol Toxicol. 2002 May;90(5):260-7.|[4]Andersson SH, et al. Biotransformation of tolterodine, a new muscarinic receptor antagonist, in mice, rats, and dogs. Drug Metab Dispos. 1998 Jun;26(6):528-35.
CAS Number
– 1217645-16-3
Molecular Weight
– 376.03
Compound Purity
– 99.0
SMILES
– [2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])N(C(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])CC[C@H](C1=CC=CC=C1)C2=C(C=CC(C)=C2)O.Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– mAChR
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
