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Products Details
Product Description
– Tolindate is a potent PXR agonist with an EC50 value of 8.3 µM. Tolindate shows antifungal activity[1][2].
Web ID
– HY-148223
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C18H19NOS
References
– [1]Lynch C, et al. Characterization of human pregnane X receptor activators identified from a screening of the Tox21 compound library. Biochem Pharmacol. 2021 Feb;184:114368.|[2]Pastor L, et al. New antifungals selected by molecular topology. Bioorg Med Chem Lett. 1998 Sep 22;8(18):2577-82.
CAS Number
– 27877-51-6
Molecular Weight
– 297.41
SMILES
– S=C(N(C)C1=CC=CC(C)=C1)OC2=CC=C3C(CCC3)=C2
Clinical Information
– No Development Reported
Research Area
– Infection; Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Fungal
Pathway
– Anti-infection
Product type
– Reference compound
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