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TNP-470
SKU
HY-101932-1 mg
Category Reference compound
Tags Aminopeptidase, Cancer; Cardiovascular Disease, Metabolic Enzyme/Protease
$280 – $1,280
Products Details
Product Description
– TNP-470 is a methionine aminopeptidase-2 inhibitor and also an angiogenesis inhibitor.
Web ID
– HY-101932
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H28ClNO6
References
– [1]Kidoikhammouan S, et al. TNP-470, a methionine aminopeptidase-2 inhibitor, inhibits cell proliferation, migration and invasion of human cholangiocarcinoma cells in vitro. Asian Pac J Cancer Prev. 2012;13 Suppl:155-60.|[2]White HM, et al. The angiogenic inhibitor TNP-470 decreases caloric intake and weight gain in high-fat fed mice. Obesity (Silver Spring). 2012 Oct;20(10):2003-9.
CAS Number
– 129298-91-5
Molecular Weight
– 401.88
Compound Purity
– 99.30
SMILES
– C[C@]1([C@@H](C/C=C(C)/C)O1)[C@]([C@@H]2OC)([H])[C@]3(CC[C@H]2OC(NC(CCl)=O)=O)CO3
Clinical Information
– Phase 2
Research Area
– Cancer; Cardiovascular Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Aminopeptidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.