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Products Details
Product Description
– TNKS-IN-2 (compound 40) is a potent and selective tankyrase (TNKS) inhibitor with pIC50 values of 8.1, 7.0 for TANKS and Wnt, respectively[1].
Web ID
– HY-117700
Shipping
– Room temperature
Molecular Formula
– C24H22N10O2
References
– [1]Thomson DW, et al. Discovery of a Highly Selective Tankyrase Inhibitor Displaying Growth Inhibition Effects against a Diverse Range of Tumor Derived Cell Lines. J Med Chem. 2017 Jul 13;60(13):5455-5471.
CAS Number
– 1584646-59-2
Molecular Weight
– 482.50
SMILES
– O=C(N1CCN(CC1)C(C2=CC=C(C=C2)NC3=NC4=C(C=CC=C4)N5C3=NN=N5)=O)C6=NN(C=C6)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PARP
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
