TNIK-IN-5

SKU HY-143437-1mg Category Tags , ,

$316

Only 1000 item(s) left in stock.

Products Details

Product Description

– TNIK-IN-5 is an efficient TNIK inhibitor with IC50 of 0.05 μM. TNIK-IN-5 efficiently inhibits Wnt signaling in intact cells. TNIK-IN-5 shows excellent in vitro anti-colorectal cancer activity[1].

Web ID

– HY-143437

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C22H17N3O3

References

– [1]Luo X, Yang R, Li Y, Zhang L, Yang S, Li L. Discovery of benzo[d]oxazol-2(3H)-one derivatives as a new class of TNIK inhibitors for the treatment of colorectal cancer. Bioorg Med Chem Lett. 2022;67:128745.

CAS Number

– 2754265-66-0

Molecular Weight

– 371.39

SMILES

– O=C1OC2=CC(C3=CN=C(NC=C4)C4=C3)=CC=C2N1CC5=CC=CC(OC)=C5

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Wnt

Pathway

– Stem Cell/Wnt

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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