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Products Details
Product Description
– TNF-alpha-IN-1 (compound 202) is an orally active inhibitor of TNF-alpha. TNF-alpha-IN-1 has anti-inflammatory activity which can used in study rheumatoid arthritis, psoriasis, and asthma[1].
Web ID
– HY-160027
Shipping
– Room temperature
Molecular Formula
– C57H57N5O8
References
– [1]Jinbo Lee, et al. Macrocyclic compounds for inhibition of tumor necrosis factor alpha. United States, US8338565B2. 2012-12-25.
Molecular Weight
– 940.09
SMILES
– O=C([C@@H](NC([C@H](NC(CCC(NC1=CC=C(C[C@H](N2)C(N[C@@H](CC3=CC=CC=C3)C(O)=O)=O)C=C1)=O)=O)CCC4=CC=CC=C4)=O)CC5=CC=C(C6=CC=CC=C6)C=C5)C[C@H](CC7=CC=CC=C7)C2=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– TNF Receptor
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
