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TMX1
$320 – $2,800
Products Details
Product Description
– TMX1 is a BRD4 covalent molecular glue degrader. TMX1 selectively recruits DCAF16 to BRD4BD2, resulting in the degradation of BRD4[1].
Web ID
– HY-153385
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H28N4O3S
References
– [1]Li Y D, et al. Template-assisted covalent modification of DCAF16 enables BRD4 molecular glue degraders[J]. Cancer Research, 2023, 83(7_Supplement): 3424-3424.
Molecular Weight
– 476.59
Compound Purity
– 99.09
SMILES
– O=C/C=C/C1=CC=C(C2=N[C@@H](CC(OC(C)(C)C)=O)C3=NN=C(C)N3C4=C2C(C)=C(C)S4)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 100 mg/mL
Target
– Apoptosis;Epigenetic Reader Domain
Pathway
– Apoptosis;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
