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TMCB
SKU
HY-103384-Get quote
Category Reference compound
Tags Cancer, Casein Kinase, Cell Cycle/DNA Damage;Stem Cell/Wnt
Products Details
Product Description
– TMCB is a selective, ATP-competitive CK2 (casein kinase II) inhibitor with distinct Ki values of 83 nM and 21 nM for the two different catalytic CK2 subunits α and α’, respectively[1].
Web ID
– HY-103384
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C11H9Br4N3O2
References
– [1]Bollacke A, Nienberg C, Borgne ML, Jose J. Toward selective CK2alpha and CK2alpha’ inhibitors: Development of a novel whole-cell kinase assay by Autodisplay of catalytic CK2alpha’. J Pharm Biomed Anal. 2016;121:253-260.
CAS Number
– 905105-89-7
Molecular Weight
– 534.82
SMILES
– O=C(C1=NCCN1)NC2=C(Br)C(Br)=C(OC)C(Br)=C2Br
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Casein Kinase
Isoform
– CK2
Pathway
– Cell Cycle/DNA Damage;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.