Download Files:
TM5007
$350
Only 1000 item(s) left in stock.
Products Details
Product Description
– TM5007 is a poent and orally active inhibitor of plasminogen activator inhibitor-1 (PAI-1) with an IC50 of 29 μM. TM5007 enhance fibrinolysis activity and inhibits coagulation. TM5007 also prevents the fibrotic process initiated by bleomycin in mouse lung[1].
Web ID
– HY-119160
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C24H20N2O6S4
References
– [1]Izuhara Y, et al. Inhibition of plasminogen activator inhibitor-1: its mechanism and effectiveness on coagulation and fibrosis. Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):672-7.
CAS Number
– 342595-05-5
Molecular Weight
– 560.69
SMILES
– O=C(NC1=C(C(O)=O)C(C2=CC=CS2)=CS1)CCCCC(NC3=C(C(O)=O)C(C4=CC=CS4)=CS3)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– PAI-1
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
