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TLR7 agonist 9
SKU
HY-152726-Get quote
Category Reference compound
Tags Cancer; Infection, Cell Cycle/DNA Damage;Immunology/Inflammation, Nucleoside Antimetabolite/Analog;Toll-like Receptor (TLR)
Products Details
Product Description
– TLR7 agonist 9 (compound 10) is an aonist of TLR7. TLR7 agonist 9 can be used for research of cancer and infectious disease[1]. TLR7 agonist 9 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-152726
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C14H17N5O7
References
– [1]Webber Stephen E, et al. TLR7 agonists for treatment of cancer and infectious disease. World Intellectual Property Organization, WO2019226977 A1. 2019-11-28. |[2]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
CAS Number
– 2389988-38-7
Molecular Weight
– 367.31
SMILES
– OC[C@@H]1[C@H](O)[C@@H](O)[C@H](N(C(N2CC#CCO)=O)C3=C2C(NC(N)=N3)=O)O1
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– 10 mM in DMSO
Target
– Nucleoside Antimetabolite/Analog;Toll-like Receptor (TLR)
Isoform
– TLR7
Pathway
– Cell Cycle/DNA Damage;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.