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Product Description
– TLR7 agonist 16 (compound 16d) is a highly potent TLR7 agonist with an EC50 of 18 nM. TLR7 agonist 16 potently induces the activation of mouse macrophages and hPBMCs at low-nanomolar concentrations[1].
Web ID
– HY-156177
Shipping
– Room temperature
Molecular Formula
– C25H29N5O2
References
– [1]Emma G DeYoung, et al. Synthesis and Optimization of 1-Substituted Imidazo[4,5-Â c]quinoline TLR7 Agonists. ACS Med Chem Lett. 2023 Sep 14;14(10):1358-1368.
CAS Number
– 2832199-56-9
Molecular Weight
– 431.53
SMILES
– O=C(OC(C)C)NC1=CC=C(CN2C(CCCC)=NC3=C2C4=CC=CC=C4N=C3N)C=C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Toll-like Receptor (TLR)
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
