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TLR7 agonist 1
$350 – $3,200
Products Details
Product Description
– TLR7 agonist 1 is a potent, selective and oral TLR7 agonist with an IC50 of 90 nM.
Web ID
– HY-111358
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C21H25N5O
References
– [1]Pieters S, et al. Discovery of selective 2,4-diaminoquinazoline toll-like receptor 7 (TLR 7) agonists. Bioorg Med Chem Lett. 2018 Feb 15;28(4):711-719.
CAS Number
– 2178156-33-5
Molecular Weight
– 363.46
Compound Purity
– 98.95
SMILES
– NC1=NC2=C(C(C(N[C@@H](C)C3=CC=CC=C3)=O)=CC=C2)C(NCCCC)=N1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : ≥ 100 mg/mL
Target
– Toll-like Receptor (TLR)
Isoform
– TLR7
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
