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TL4830031
$980 – $1,500
Products Details
Product Description
– TL4830031 (compound 8i), a quinolone antibiotic derivatives, is a potent Axl inhibitor with an IC50 value of 26 nM. TL4830031 inhibits the phosphorylation of Axl. TL4830031 inhibits cell invasion and migration. TL4830031 can be used for cancer research[1].
Web ID
– HY-150041
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C35H33F2N5O6
References
– [1]Tan L, et, al. Quinolone antibiotic derivatives as new selective Axl kinase inhibitors. Eur J Med Chem. 2019 Mar 15;166:318-327.
CAS Number
– 2084107-15-1
Molecular Weight
– 657.66
Compound Purity
– 98.0
SMILES
– O=C(C1=CN2C3=C(CCC2C)C(N4CCC(CC4)O)=C(F)C=C3C1=O)NC5=CC=C(C(F)=C5)OC6=NC=NC7=C6C=C(OC)C(OC)=C7
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 2.38 mg/mL (ultrasonic;warming;adjust pH to 5 with HCl;heat to 60°C)
Target
– TAM Receptor
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
