Download Files:
Tizanidine-d4
$140 – $1,050
Products Details
Product Description
– Tizanidine-d4 is the deuterium labeled Tizanidine. Tizanidine is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons[1][2].
Web ID
– HY-B0194S
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C9H4D4ClN5S
References
– [1]Kamen L, et al. A practical overview of tizanidine use for spasticity secondary to multiple sclerosis, stroke, and spinal cord injury. Curr Med Res Opin. 2008 Feb;24(2):425-39.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 1188331-19-2
Molecular Weight
– 257.74
Compound Purity
– 99.93
SMILES
– N(C=1C=2C(C=CC1Cl)=NSN2)C=3NC(C(N3)([2H])[2H])([2H])[2H]
Clinical Information
– No Development Reported
Research Area
– Neurological Disease; Endocrinology; Cancer
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
