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Product Description
– Tirilazad is a nonglucocorticoid, 21-aminosteroid that inhibits lipid peroxidation. Tirilazad can attenuate brain or spinal cord injury caused by trauma, stroke, ischemia and reperfusion injury. Tirilazad has antiviral activities against nCoV. Tirilazad is neuroprotective for ischaemic stroke, can be used for subarachnoid hemorrhage research[1][2][3].
Web ID
– HY-132280
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C38H52N6O2
References
– [1]Bath PM, et al. Tirilazad for acute ischaemic stroke. Cochrane Database Syst Rev. 2001;(4):CD002087.|[2]Zhang S, et al. Tirilazad for aneurysmal subarachnoid haemorrhage. Cochrane Database Syst Rev. 2010 Feb 17;(2):CD006778.|[3]Tirilazad mesylate in acute ischemic stroke: A systematic review. Tirilazad International Steering Committee. Stroke. 2000 Sep;31(9):2257-65.
CAS Number
– 110101-66-1
Molecular Weight
– 624.86
SMILES
– C[C@@]12[C@](C[C@H]([C@@H]2C(CN3CCN(C4=NC(N5CCCC5)=NC(N6CCCC6)=C4)CC3)=O)C)([H])[C@@]7([H])C([C@@]8(C(CC7)=CC(C=C8)=O)C)=CC1
Clinical Information
– Phase 3
Research Area
– Infection; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Antibiotic
Pathway
– Anti-infection
Product type
– Reference compound
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