TIQ-A

$95$650

Products Details

Product Description

– TIQ-A is a potent TNKS (poly-ART, PARP) inhibitor, with an IC50 of 24 nM for TNKS2. TIQ-A is a potential anti-ischemic agent[1].

Web ID

– HY-121719

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C11H7NOS

References

– [1]Maksimainen MM, et al. Analogs of TIQ-A as inhibitors of human mono-ADP-ribosylating PARPs. Bioorg Med Chem. 2021 Dec 15;52:116511.

CAS Number

– 420849-22-5

Molecular Weight

– 201.24

Compound Purity

– 99.65

SMILES

– O=C1NC2=C(C3=C1C=CC=C3)C=CS2

Clinical Information

– No Development Reported

Research Area

– Cancer; Cardiovascular Disease

Solubility

– DMSO : 125 mg/mL (ultrasonic)

Target

– PARP

Isoform

– PARP10;PARP14;PARP15;PARP2;TNKS2/PARP5B

Pathway

– Cell Cycle/DNA Damage;Epigenetics

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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