Tin protoporphyrin IX dichloride

$130$210

Products Details

Product Description

– Tin protoporphyrin IX dichloride (SnPPIX) is a potent Heme oxygenase-1 (HO-1) inhibitor. Tin protoporphyrin IX dichloride sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice model[1].

Web ID

– HY-101194

Storage Temperature

– -20°C (Powder, sealed storage, away from moisture)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C34H32Cl2N4O4Sn

References

– [1]Abdalla MY,et al.Enhancing responsiveness of pancreatic cancer cells to gemcitabine treatment under hypoxia by heme oxygenase-1 inhibition.Transl Res. 2019 May;207:56-69.

CAS Number

– 14325-05-4

Molecular Weight

– 750.26

Compound Purity

– 95.0

SMILES

– [Cl-][Sn+4]123([N-]4C5=C(CCC(O)=O)C(C)=C4C=C(C(C=C)=C6C)[N]1=C6C=C(C(C=C)=C7C)[N-]2C7=CC(C(C)=C8CCC(O)=O)=[N]3C8=C5)[Cl-]

Clinical Information

– Phase 2

Research Area

– Cancer

Solubility

– 0.1 M NaOH : 14.29 mg/mL (ultrasonic;adjust pH to 12 with NaOH)|1M NaOH : 5 mg/mL (ultrasonic)|DMF : 1 mg/mL (ultrasonic;warming)|DMSO : 0.5 mg/mL (ultrasonic;warming)

Target

– Reactive Oxygen Species

Pathway

– Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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