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Tigecycline
$42 – $605
Products Details
Product Description
– Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline for E. coli (MG1655 strain) is approximately 125 ng/mL[1]. MIC50 and MIC90 are 1 and 2 mg/L for Acinetobacter baumannii (A. baumannii), respectively[2].
Web ID
– HY-B0117
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C29H39N5O8
Citations
– Animal Diseases. 02 November 2021.|Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00470-19.|Antimicrob Agents Chemother. 2023 Jan 23;e0145922.|Biomed Pharmacother. 2023 Nov 8:115856.|Clin Exp Pharmacol Physiol. 2023 Apr 22.|EBioMedicine. 2022 Apr;78:103943.|Infect Drug Resist. 2020 Jul 28;13:2617-2629.|Infect Drug Resist. 2021 Jun 30;14:2499-2507.|Infect Drug Resist. 2023 Apr 17.|Int J Antimicrob Agents. 2018 Aug;52(2):269-271.|J Antibiot (Tokyo). 2022 Jun 27.|Microb Pathog. 2020 Dec;149:104502.|Microbiol Spectr. 2022 Dec 8;e0323822.|Microbiol Spectr. 2023 May 4;e0071823.|Nat Commun. 2022 Mar 2;13(1):1116.|SLAS Discov. 2020 Sep;25(8):895-905.|Ann Lab Med. 2021 May 1;41(3):293-301.
References
– [1]Jitkova Y, et al. A novel formulation of tigecycline has enhanced stability and sustained antibacterial and antileukemic activity. PLoS One. 2014 May 28;9(5):e95281.|[2]Falagas ME, et al. Activity of TP-6076 against carbapenem-resistant Acinetobacter baumannii isolates collected from inpatients in Greek hospitals. Int J Antimicrob Agents. 2018 Aug;52(2):269-271.
CAS Number
– 220620-09-7
Molecular Weight
– 585.65
Compound Purity
– 99.95
SMILES
– O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])CC4=C(C(C3=C(O)[C@@]21O)=O)C(O)=C(NC(CNC(C)(C)C)=O)C=C4N(C)C)N
Clinical Information
– Launched
Research Area
– Infection; Cancer
Solubility
– DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 8.33 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Antibiotic;Autophagy;Bacterial
Pathway
– Anti-infection;Autophagy
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
