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Product Description
– Tie2 kinase inhibitor 2 (compound 7) is a selective Tie2 kinase inhibitor with an IC50 value of 1 μM. Tie2 kinase inhibitor 2 inhibits endothelial cell tube formation, and can be used for Tie2-mediated angiogenic disorders research[1].
Web ID
– HY-113571
Shipping
– Room temperature
Molecular Formula
– C31H35N3O5
References
– [1]Jinqi Liu, et al. Identification and characterization of small-molecule inhibitors of Tie2 kinase. FEBS Lett. 2008 Mar 5;582(5):785-91.
CAS Number
– 1020412-97-8
Molecular Weight
– 529.63
SMILES
– O=C(C1=CC(C2=CC=C(CN(CC(N[C@H](C3CCCCC3)C)=O)C(OC4=CC=C(C)C=C4)=O)C=C2)=CN=C1)O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Tie
Isoform
– Tie2
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
