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Thymidine 3′,5′-disphosphate
Products Details
Product Description
– Thymidine 3′,5′-disphosphate (Deoxythymidine 3′,5′-diphosphate; pdTp) is a selective small molecule inhibitor of staphylococcal nuclease and tudor domain containing 1 (SND1, the miRNA regulatory complex RISC subunit) and inhibits SND1 activity. Thymidine 3′,5′-disphosphate exhibits anti-tumor efficacy in vivo[1].
Web ID
– HY-115581
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C10H16N2O11P2
References
– [1]Nidhi Jariwala, et al. Oncogenic Role of SND1 in Development and Progression of Hepatocellular Carcinoma. Cancer Res. 2017 Jun 15;77(12):3306-3316.
CAS Number
– 2863-04-9
Molecular Weight
– 402.19
SMILES
– OP(O)(O[C@H]1C[C@H](N2C(NC(C(C)=C2)=O)=O)O[C@@H]1COP(O)(O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
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