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Products Details
Product Description
– THK-523 has demonstrated its high affinity and selectivity for tau pathology both in vitro and in vivo. 18F-THK523 is a potent tau imaging radiotracer. 18F-THK523 is a potent in vivo tau imaging ligand for Alzheimer’s disease[1].
Web ID
– HY-100723
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C17H15FN2O
References
– [1]Ryuichi Harada, et al. Comparison of the binding characteristics of [<sup>18</sup>F]THK-523 and other amyloid imaging tracers to Alzheimer’s disease pathology. Eur J Nucl Med Mol Imaging. 2013 Jan;40(1):125-32.|[2]Michelle T Fodero-Tavoletti, 18F-THK523: a novel in vivo tau imaging ligand for Alzheimer’s disease. Brain. 2011 Apr;134(Pt 4):1089-100.
CAS Number
– 1573029-17-0
Molecular Weight
– 282.31
SMILES
– NC1=CC=C(C2=NC3=CC=C(OCCF)C=C3C=C2)C=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Amyloid-β
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
