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Thioquinapiperifil
SKU
HY-119611-Get quote
Category Reference compound
Tags Endocrinology; Metabolic Disease, Metabolic Enzyme/Protease, Phosphodiesterase (PDE)
Products Details
Product Description
– Thioquinapiperifil (KF31327 free base), a potent, selective and non-competitive phosphodiesterase-5 (PDE-5, IC50 of 0.074 nM) inhibitor, is used for sexual enhancement study[1][2].
Web ID
– HY-119611
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C24H28N6OS
References
– [1]Nahoko Uchiyama, et al. Determination of a new type of phosphodiesterase-5 inhibitor, thioquinapiperifil, in a dietary supplement promoted for sexual enhancement. Chem Pharm Bull (Tokyo). 2008 Sep;56(9):1331-4.|[2]R Hirose, et al. KF31327, a new potent and selective inhibitor of cyclic nucleotide phosphodiesterase 5. Eur J Pharmacol. 2001 Nov 9;431(1):17-24.
CAS Number
– 220060-39-9
Molecular Weight
– 448.58
SMILES
– S=C1NC2=CC3=C(NCC4=CC=CC=C4N5CCC(CO)CC5)N=CN=C3C=C2N1CC
Clinical Information
– No Development Reported
Research Area
– Endocrinology; Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Phosphodiesterase (PDE)
Isoform
– PDE1;PDE2;PDE3;PDE4;PDE5
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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