Thiocolchicoside

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Products Details

Product Description

– Thiocolchicoside is a competitive γ-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist in the central nervous system. Thiocolchicoside is a semisynthetic sulfur derivative of colchicoside. Thiocolchicoside is a muscle relaxant and has anti-inflammatory, and analgesic properties[1].

Web ID

– HY-N0301

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C27H33NO10S

References

– [1]Carta M, et al. The muscle relaxant thiocolchicoside is an antagonist of GAB<sub>A</sub>A receptor function in the central nervous system. Neuropharmacology. 2006 Sep;51(4):805-15.

CAS Number

– 602-41-5

Molecular Weight

– 563.62

Compound Purity

– 99.54

SMILES

– CSC1=CC=C2C3=C(OC)C(OC)=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=C3CC[C@H](NC(C)=O)C2=CC1=O

Clinical Information

– Phase 4

Research Area

– Inflammation/Immunology; Neurological Disease

Solubility

– DMSO : 250 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)

Target

– GABA Receptor

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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