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Thiacloprid-d4
SKU
HY-B1953S-Get quote
Category Isotope-Labeled Compounds
Tags Anti-infection;Cell Cycle/DNA Damage, DNA Stain;Parasite, Infection
Products Details
Product Description
– Thiacloprid-d4 is the deuterium labeled Thiacloprid[1]. Thiacloprid, a chloronicotinyl insecticide, is targeted chiefly to control aphid pest species in orchards and vegetables[1]. Thiacloprid destabilizes DNA. Thiacloprid changes the structure and stability of DNA through binding into the minor groove by hydrophobic or hydrogen interactions[2].
Web ID
– HY-B1953S
Shipping
– Room temperature
Molecular Formula
– C10H5D4ClN4S
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Schuld, M., et al. Effects of Thiacloprid, a New Chloronicotinyl Insecticide, On the Egg Parasitoid Trichogramma cacaoeciae. Ecotoxicology 9, 197–205 (2000).|[3]Verebová V, Želonková K, Holečková B, Staničová J. The effect of neonicotinoid insecticide thiacloprid on the structure and stability of DNA. Physiol Res. 201968(Suppl 4):S459-S466.
CAS Number
– 1793071-39-2
Molecular Weight
– 256.75
SMILES
– N#C/N=C(SC([2H])([2H])C1([2H])[2H])/N1CC2=CN=C(Cl)C=C2
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– DNA Stain;Parasite
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Isotope-Labeled Compounds
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