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Thalidomide-O-PEG4-amine (TFA)
SKU
HY-141010B-Get quote
Category Reference compound
Tags Cancer, E3 Ligase Ligand-Linker Conjugates, PROTAC
Products Details
Product Description
– Thalidomide-O-PEG4-amine TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Web ID
– HY-141010B
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H32F3N3O11
References
– [1]Zhang NN, et al. A Thermostable mRNA Vaccine against COVID-19. Cell. 2020;182(5):1271-1283.e16.
CAS Number
– 2934561-88-1
Molecular Weight
– 607.53
SMILES
– O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3OCCOCCOCCOCCOCCN)=O.O=C(O)C(F)(F)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– Cereblon
Pathway
– PROTAC
Product type
– Reference compound
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