TG100-115

$106$515

Products Details

Product Description

– TG100-115 is a selective PI3Kγ/PI3Kδ inhibitor with IC50s of 83 and 235 nM, respectively.

Web ID

– HY-10111

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C18H14N6O2

References

– [1]Doukas J, et al. Phosphoinositide 3-kinase gamma/delta inhibition limits infarct size after myocardial ischemia/reperfusion injury. Proc Natl Acad Sci U S A. 2006 Dec 26;103(52):19866-71.

CAS Number

– 677297-51-7

Molecular Weight

– 346.34

Compound Purity

– 99.01

SMILES

– NC1=C(C(N=C2C3=CC(O)=CC=C3)=NC(N)=N1)N=C2C4=CC(O)=CC=C4

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease; Cancer

Solubility

– DMSO : 33.33 mg/mL (ultrasonic;warming;adjust pH to 2 with HCl;heat to 60°C)

Target

– PI3K

Isoform

– PI3Kγ;PI3Kδ

Pathway

– PI3K/Akt/mTOR

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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