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Products Details
Product Description
– Tenofovir-C3-O-C15-CF3 (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo.
Web ID
– HY-139721
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C28H52F3N6O5P
References
– [1]Pribut N, et al. ω-Functionalized Lipid Prodrugs of HIV NtRTI Tenofovir with Enhanced Pharmacokinetic Properties. J Med Chem. 2021 Sep 9;64(17):12917-12937.
CAS Number
– 2611373-80-7
Molecular Weight
– 640.72
SMILES
– FC(F)(F)CCCCCCCCCCCCCCCOCCCOP(CO[C@H](C)CN1C=NC2=C1N=CN=C2N)([O-])=O.[NH4+]
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HIV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
