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Products Details
Product Description
– Tenacigenin B is a steroid that can be isolated from the genus Alocasia. Tenacigenin B has anti-tumor effects on lymphoma via regulation of Aurora-A[1][2].
Web ID
– HY-N1168
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C21H32O5
References
– [1]Peng W, et al. The cytotoxic and tyrosine kinase inhibitory properties of C21 steroids and iridoids from the tubers of Alocasia cucullata. J Nat Med. 2016 Jul;70(3):602-9.|[2]Dai X, et al. Tenacigenin B Has Anti-Tumor Effect in Lymphoma by In Vitro and In Vivo Study. Med Sci Monit. 2019 Sep 1;25:6563-6573.
CAS Number
– 80508-42-5
Molecular Weight
– 364.48
SMILES
– C[C@@]12[C@]3(CC[C@H]2C(C)=O)[C@]4([C@@]([C@@H]([C@H]1O)O)([H])[C@@]5([C@@](C[C@H](CC5)O)([H])CC4)C)O3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Aurora Kinase
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
