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Product Description
– Telavancin (TD-6424) is a semisynthetic lipoglycopeptide vancomycin-derivative, is a novel antimicrobial agent developed by Theravance for overcoming resistant Gram-positive bacterial infections, specifically methicillin-resistant Staphylococcus aureus (MRSA). Telavancin disrupts cell membrane integrity, can be used for research of complicated skin and skin structure infections (cSSSIs) caused by Gram-positive bacteria[1].
Web ID
– HY-112959
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C80H106Cl2N11O27P
References
– [1]Das B, et al. Telavancin: a novel semisynthetic lipoglycopeptide agent to counter the challenge of resistant Gram-positive pathogens. Ther Adv Infect Dis. 2017 Mar;4(2):49-73.Â
CAS Number
– 372151-71-8
Molecular Weight
– 1755.63
SMILES
– ClC1=CC([C@H]([C@](C(N[C@@H]2C(O)=O)=O)([H])N3)O)=CC=C1OC4=CC([C@](NC([C@@H](NC5=O)CC(N)=O)=O)([H])C(N[C@](C3=O)([H])C(C=C6C(C2=CC(O)=C7CNC[P](O)(O)=O)=C7O)=CC=C6O)=O)=CC(OC8=CC=C([C@H]([C@H]5NC([C@H](NC)CC(C)C)=O)O)C=C8Cl)=C4O[C@H](O[C@@H]9CO)[C@@H]([C@H]([C@@H]9O)O)O[C@H](O[C@H]%10C)C[C@@](C)([C@@H]%10O)NCCNCCCCCCCCCC
Clinical Information
– Launched
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Bacterial
Isoform
– Glycopeptide
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
