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Products Details
Product Description
– Tebufelone (NE-11740), a nonsteroidal anti-inflammatory drug (NSAID), is a selective dual COX-2/5-lipoxygenase inhibitor. Tebufelone displays potent anti-inflammatory, analgesic and anti-pyretic properties[1][2].
Web ID
– HY-106823
Shipping
– Room temperature
Molecular Formula
– C20H28O2
References
– [1]S M Weisman, et al. Effects of tebufelone (NE-11740), a new anti-inflammatory drug, on arachidonic acid metabolism. Agents Actions. 1994 May;41(3-4):156-63. |[2]Sebastian Braun, et al. Carborane-Based Tebufelone Analogs and Their Biological Evaluation In Vitro. ChemMedChem. 2023 Jul 17;18(14):e202300206.
CAS Number
– 112018-00-5
Molecular Weight
– 300.44
SMILES
– OC1=C(C=C(C(CCCC#C)=O)C=C1C(C)(C)C)C(C)(C)C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– COX;Lipoxygenase
Isoform
– 5-LOX;COX-2
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease
Product type
– Reference compound
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