TDI-011536

$65$550

Products Details

Product Description

– TDI-011536 is a potent Lats kinase inhibitor, interrupts Hippo-Yap signaling and initiates the proliferation of lesioned heartmuscle cells. TDI-011536 can be used in studies of organ conservation and regeneration[1].

Web ID

– HY-150042

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C19H16N4O2S

References

– [1]Kastan NR, et al. Development of an improved inhibitor of Lats kinases to promote regeneration of mammalian organs. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2206113119.

CAS Number

– 2687970-96-1

Molecular Weight

– 364.42

Compound Purity

– 99.91

SMILES

– O=C(C1=CNC2=NC=CC=C12)/N=C(SC=C3CO)/N3CC4=CC=CC=C4

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease; Others

Solubility

– DMSO : 125 mg/mL (ultrasonic)

Target

– YAP

Pathway

– Stem Cell/Wnt

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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