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TCS 401
$132 – $1,080
Products Details
Product Description
– TCS 401 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B).
Web ID
– HY-12312
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C10H11ClN2O5S
References
– [1]Ponnusamy M, et al. Necrotic renal epithelial cell inhibits renal interstitial fibroblast activation: role of protein tyrosine phosphatase 1B. Am J Physiol Renal Physiol. 2013 Mar 15;304(6):F698-709.|[2]Du ZD, et al. Protein tyrosine phosphatase 1B regulates the activity of retinal pigment epithelial cells. Mol Vis. 2015 May 1;21:523-31.
CAS Number
– 243966-09-8
Molecular Weight
– 306.72
Compound Purity
– 98.0
SMILES
– O=C(C1=C(NC(C(O)=O)=O)SC2=C1CCNC2)O.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 0.1 M NaOH : 6.67 mg/mL (ultrasonic;adjust pH to 9 with NaOH)
Target
– Phosphatase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
