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Products Details
Product Description
– TC113 is a c(RGDyK)-Based conjugate of Gemcitabine (GEM). TC113 could be internalized by A549 cells through integrin αvβ3. TC113 shows potent antiproliferative properties against WM266.4 and A549 cells[1].
Web ID
– HY-145314
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C37H50F2N12O13
References
– [1]Chatzisideri T, et al. Integrin-Mediated Targeted Cancer Therapy Using c(RGDyK)-Based Conjugates of Gemcitabine. J Med Chem. 2022;65(1):271-284.
Molecular Weight
– 908.86
SMILES
– FC1(F)[C@H](O)[C@@H](COC(NCCCC[C@@H](C(N[C@@H](CCCNC(N)=N)C(NC2)=O)=O)NC([C@H](NC([C@@H](NC2=O)CC(O)=O)=O)CC3=CC=C(O)C=C3)=O)=O)O[C@H]1N4C=CC(N)=NC4=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Integrin
Pathway
– Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
