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TC OT 39

$514$823

Products Details

Product Description

– TC OT 39 is a synthetic oxytocin analog, as well as a selective agonist of oxytocin receptor (OXTR, EC50=180 nM). TC OT 39 is also an Avprla vasopressin receptor antagonist with an Ki value of 330 nM. TC OT 39 exhibits sedative effects in mouse models[1].

Web ID

– HY-108678

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C32H40N8O2S

References

– [1]Moy SS, et al. Prosocial effects of an oxytocin metabolite, but not synthetic oxytocin receptor agonists, in a mouse model of autism. Neuropharmacology. 2019 Jan;144:301-311.

CAS Number

– 479232-57-0

Molecular Weight

– 600.78

SMILES

– O=C(N1[C@H](C(N2CCN(C)CCC2)=S)CCC1)NCC3=CC=C(C(N4CC5=C(N(C)N=C5)NC6=CC=CC=C46)=O)C=C3C

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Oxytocin Receptor;Vasopressin Receptor

Isoform

– V1a Receptor 

Pathway

– GPCR/G Protein

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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