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Products Details
Product Description
– TC AC 28 is a high-affinity BET bromodomain ligand with Kd values of 40, 800 nM for Brd2(2), Brd2(1), respectively[1].
Web ID
– HY-121738
Shipping
– Room temperature
Molecular Formula
– C23H21N5O3
References
– [1]Khan R, et al. Gram-Scale Laboratory Synthesis of TC AC 28, a High-Affinity BET Bromodomain Ligand. ACS Omega. 2017 Aug 8;2(8):4328-4332.
CAS Number
– 1809296-92-1
Molecular Weight
– 415.44
SMILES
– COC(CC1N=C(C2=C3C=CNC3=CC=C2)C4=CC(OC)=CC=C4N5C(C)=NN=C15)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Isoform
– BRD2
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
