Download Files:
Products Details
Product Description
– TBK1/IKKε-IN-6 (example 110) is a TBK1 and IKKε inhibitor, with IC50 values of <100 nM for both TBK1 and IKKε[1].
Web ID
– HY-138931
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C31H36F2N8O4
References
– [1]PERRIOR, et al. Pyrimidine compounds as inhibitors of protein kinases ikk epsilon and/or tbk-1, processes for their preparation, and pharmaceutical compositions containing them. WO2019079373 A1.
CAS Number
– 2306877-20-1
Molecular Weight
– 622.67
SMILES
– COC1=C(N2[C@@H](CN(CC2)C)C)C=CC(NC3=NC=CC(C4=CC(C#N)=C(C=C4)OC5C(F)(CN(CC5)C([C@H](O)C)=O)F)=N3)=N1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– IKK
Pathway
– NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
