Download Files:
Tazemetostat de(methylene morpholine)-O-C3-O-C-COOH
$450 – $3,800
Products Details
Product Description
– Tazemetostat de(methylene morpholine)-O-C3-O-C-COOH (Compound 21b) is an EZH2 degrader and can be used for the research of lymphoma[1].
Web ID
– HY-147090
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Molecular Formula
– C34H43N3O7
References
– [1]Tu Y, et al. Design, Synthesis, and Evaluation of VHL-Based EZH2 Degraders to Enhance Therapeutic Activity against Lymphoma. J Med Chem. 2021 Jul 22;64(14):10167-10184.
CAS Number
– 2750350-39-9
Molecular Weight
– 605.72
Compound Purity
– 98.24
SMILES
– O=C(COCCCOC1=CC=C(C2=CC(C(NCC3=C(C)C=C(C)NC3=O)=O)=C(C)C(N(C4CCOCC4)CC)=C2)C=C1)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 160 mg/mL
Target
– Histone Methyltransferase
Isoform
– EZH2
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
