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Products Details
Product Description
– Taxinine B is a taxoid that can be isolated from Japanese Yew Taxus Cuspid. Taxinine B inhibits CaCl2-induced depolymerization of microtubule. Taxinine B is useful for overcoming multidrug resistance in tumor cells[1].
Web ID
– HY-N1171
Shipping
– Room temperature
Molecular Formula
– C37H44O11
References
– [1]JunÃchi Kobayashi, et al. Taxuspines A ∼ C, new taxoids from Japanese yew Taxus cuspidata inhibiting drug transport activity of P-glycoprotein in multidrug-resistant cells. Tetrahedron. 1994. 50 (25), 7401-7416.
CAS Number
– 18457-44-8
Molecular Weight
– 664.74
SMILES
– O=C(O[C@H](C1=C)C[C@H](OC(C)=O)[C@]([C@@H](OC(C)=O)[C@H](OC(C)=O)C2=C3C)(C)[C@]1([H])[C@H](OC(C)=O)[C@](C2(C)C)([H])CC3=O)/C=C/C4=CC=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
