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Taurocholic acid
$70 – $250
Products Details
Product Description
– Taurocholic acid (N-Choloyltaurine) has marked bioactive effects such as an inhibitory potential against hepatic artery ligation induced biliary damage by upregulation of VEGF-A expression. Taurocholic acid has immunoregulation effect[1].
Web ID
– HY-B1788
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C26H45NO7S
Citations
– Antiviral Res. 2019 Jun 27;169:104544.|Research (Wash D C). 2022 Nov 2;2022:9784081.|Research Square Print. 2022 Aug.|Biomolecules. 2022, 12(8), 1063.|RSC Adv. 2018 8:8469-8483.|FASEB J. 2022 May;36(5):e22305.
References
– [1]Mooranian A, et al. The effect of a tertiary bile acid, taurocholic acid, on the morphology and physical characteristics of microencapsulated probucol: potential applications in diabetes: a characterization study. Drug Deliv Transl Res. 2015 Oct;5(5):511-22.|[2]Xun Z,et al. Taurocholic acid inhibits the response to interferon-α therapy in patients with HBeAg-positive chronic hepatitis B by impairing CD8+ T and NK cell function. Cell Mol Immunol. 2021 Feb;18(2):461-471. |[3]Glaser S, et al. Taurocholic acid prevents biliary damage induced by hepatic artery ligation in cholestatic rats. Dig Liver Dis. 2010 Oct;42(10):709-17.
CAS Number
– 81-24-3
Molecular Weight
– 515.70
Compound Purity
– 99.18
SMILES
– O[C@H](C[C@]1([H])C[C@@H]2O)[C@@]([C@@](C[C@@H]3O)([H])[C@]1(CC2)C)([H])[C@@](CC[C@]4([H])[C@H](C)CCC(NCC[S](=O)(O)=O)=O)([H])[C@@]43C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Target
– Endogenous Metabolite
Isoform
– Human Endogenous Metabolite;Microbial Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
