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Products Details
Product Description
– tau/Aβ40 aggregation-IN-1 (Compound 20) is a tau and Aβ40 aggregation inhibitor with IC50s of 1.8 μM and 1.3 μM, respectively[1].
Web ID
– HY-149272
Shipping
– Room temperature
Molecular Formula
– C23H28N2O2S
References
– [1]Tonelli M, et al. Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer’s disease. Eur J Med Chem. 2023 Mar 15;250:115169.
Molecular Weight
– 396.55
SMILES
– COC1=CC=C2SC3=C(C(NCCC4CCN(CC4)C)=CC=C3C)C(C2=C1)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Amyloid-β;Cholinesterase (ChE);Tau Protein
Isoform
– AChE;BChE
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
