Products Details

Product Description

– TASP0433864 is a selective positive allosteric modulator (PAM) of metabotropic glutamate 2 (mGlu2) receptor with EC50 values of 199 nM and 206 nM against human and rat mGlu2 receptors, respectively. TASP0433864 has antipsychotic activity[1].

Web ID

– HY-116855

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C18H23N3O3

References

– [1]Hiyoshi T, et al. Neurophysiologic and antipsychotic profiles of TASP0433864, a novel positive allosteric modulator of metabotropic glutamate 2 receptor. J Pharmacol Exp Ther. 2014 Dec;351(3):642-53.

CAS Number

– 1431980-60-7

Molecular Weight

– 329.39

SMILES

– O=C(C1=C(C)N2C(O[C@H](COC3=CC=C(C(C)(C)C)C=C3)C2)=N1)N

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– mGluR

Isoform

– mGluR2

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

My Cart
Close Wishlist
Close Recently Viewed
Categories

Please fill out this form to request the file. We will send it to your Email address shortly. Thanks.

Please enable JavaScript in your browser to complete this form.

=

Please fill out this form to request the pricing.
We will send it to your email address shortly.
Thanks.

Please enable JavaScript in your browser to complete this form.

=