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TASP0390325
$150 – $1,550
Products Details
Product Description
– TASP0390325 is a high affinity and orally active arginine vasopressin receptor 1B (V1B receptor) antagonist with antidepressant and anxiolytic activities[1].
Web ID
– HY-117820
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C25H30Cl2FN5O4
References
– [1]M Iijima, et al. Antidepressant and anxiolytic profiles of newly synthesized arginine vasopressin V1B receptor antagonists: TASP0233278 and TASP0390325. Br J Pharmacol. 2014 Jul;171(14):3511-25.|[2]Kazumi Koga, et al. High-Contrast PET Imaging of Vasopressin V 1B Receptors with a Novel Radioligand, <sup>11</sup>C-TASP699. J Nucl Med. 2017 Oct;58(10):1652-1658.
CAS Number
– 1642187-96-9
Molecular Weight
– 554.44
Compound Purity
– 99.0
SMILES
– O=C(CN1C(C2=CC(OCCCN3CCOCC3)=CN=C2N=C1C4=CC=C(C(Cl)=C4)F)=O)NC(C)C.Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Vasopressin Receptor
Isoform
– V1b ReceptorÂ
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
